Scientist, T Cell Engineering
AstraZeneca

Gaithersburg, Maryland

Posted in Pharmaceuticals


This job has expired.

Job Info


Scientist, T Cell Engineering

Gaithersburg, MD

Do you have expertise in, and passion for CAR-T design and engineering? Would you like to apply your expertise to shape the next generation of technologies for CAR-T cell therapies in a company that follows the science and turns ideas into life-changing medicines? Then AstraZeneca might be the one for you!

It AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

AstraZeneca seeks an innovative and highly motivated Scientist with a background in immunology, molecular biology, biochemistry or a related field to join the Oncology Cell Therapy team in Gaithersburg, MD.

A major focus of the Oncology Cell Therapy team in the Cell Therapeutics and Viral Technologies group is to leverage protein engineering to control the biology of CAR-T cell therapeutics. We work closely and collaboratively with colleagues who specialize in tumor biology and immunology, T cell biology, gene editing, and high-throughput screening technologies as well as cell product manufacturing in an exciting and newly formed Oncology Cell Therapy Unit within AstraZeneca. Your expertise will be leveraged to help develop new cell therapy technologies as well as advance pipeline programs.

What you'll do

  • Design, produce and deliver lentiviral vectors for T cell engineering
  • Perform cell-based assays to characterize CAR-T cell function using flow cytometry
  • Support the development of next generation technologies for CAR-T therapy
  • Present and communicate projects with colleagues inside or outside the group.
  • Ensures work is aligned with Good Laboratory Practice, Safety, Health, and Environment standards as well as all AstraZeneca standards and external regulations.

Educational Requirements:
  • Bachelor's degree with 3+ years of relevant work experience or Master's degree with 1+ years of relevant work experience.

Required Skills:
  • Flow cytometry experience.
  • Molecular cloning skills, including PCR, DNA/RNA purifications.
  • Familiarity with viral or non-viral gene delivery into primary human cells or cell lines.
  • Strong communication skills and ability to learn quickly, multi-task and manage shifting priorities.

Additional Desirable Skills
  • Background in immunology or cell biology is highly desired
  • Experience working with in vivo animal models.
  • Experience with data analysis using R/Python is a plus
  • Broader experience of design and optimization of TCR/CAR-T, CAR-NK or TIL therapies

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what's next?

Are you already imagining yourself joining our team? Good! We can't wait to hear from you!

If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: September 26, 2022

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.


This job has expired.

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