Scientist - Clinical Virology

Gaithersburg, Maryland

Posted in Pharmaceuticals

Job Info

Main Duties and Responsibilities

This job is a lab-based research role. The work will be focused heavily upon molecular viral surveillance and resistance monitoring for the AZ infection franchise. A background in molecular/clinical virology and/or vaccinology is required

  • Rescue and characterize pseudoviruses and/or RNA viruses
  • Apply molecular biology skills to generate recombinant proteins and viruses
  • Execute biochemical and cell-based assays to characterize candidate or authorized vaccines and mAbs for SARS-CoV-2, RSV, and other viral pathogens
  • Assist in the preparation and review of bioanalytical data and reports suitable for regulatory submission
  • Communicate across the team and with senior management

Education & Experience Requirements:

Bachelor's Degree in virology, molecular biology, immunology, or another related field with 2+ years of relevant industrial (preferred) or academic experience or a Master's Degree with some relevant experience.

Essential Requirements
  • Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR.
  • Experience in cell culture, viral propagation, and viral titration.
  • Ability to evaluate data quality, troubleshoot, and interpret experimental results
  • Meticulous tracking and documenting of results in laboratory notebooks, databases, and scientific reports
  • Strong verbal and written communication skills

Desirable Requirements
  • Hands-on experience with paramyxoviruses and coronaviruses
  • Understanding of molecular cloning techniques and vector engineering
  • Understanding of DNA sequencing techniques (NGS and Sanger) and sequence analysis
  • Experience in the handling/processing of clinical specimens

AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants. Accordingly, AstraZeneca requires all US employees to be fully vaccinated for COVID-19 prior to the first date of employment. AstraZeneca will consider requests for reasonable accommodations as required by applicable law.

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