This job is a lab-based research role. The work will be focused heavily upon molecular viral surveillance and resistance monitoring for the AZ infection franchise. A background in molecular/clinical virology and/or vaccinology is required
Rescue and characterize pseudoviruses and/or RNA viruses
Apply molecular biology skills to generate recombinant proteins and viruses
Execute biochemical and cell-based assays to characterize candidate or authorized vaccines and mAbs for SARS-CoV-2, RSV, and other viral pathogens
Assist in the preparation and review of bioanalytical data and reports suitable for regulatory submission
Communicate across the team and with senior management
Education & Experience Requirements:
Bachelor's Degree in virology, molecular biology, immunology, or another related field with 2+ years of relevant industrial (preferred) or academic experience or a Master's Degree with some relevant experience.
Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR.
Experience in cell culture, viral propagation, and viral titration.
Ability to evaluate data quality, troubleshoot, and interpret experimental results
Meticulous tracking and documenting of results in laboratory notebooks, databases, and scientific reports
Strong verbal and written communication skills
Hands-on experience with paramyxoviruses and coronaviruses
Understanding of molecular cloning techniques and vector engineering
Understanding of DNA sequencing techniques (NGS and Sanger) and sequence analysis
Experience in the handling/processing of clinical specimens
AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants. Accordingly, AstraZeneca requires all US employees to be fully vaccinated for COVID-19 prior to the first date of employment. AstraZeneca will consider requests for reasonable accommodations as required by applicable law.