Research Technician
The University of Chicago

Chicago, Illinois

Posted in Education and Training

This job has expired.

Job Info


BSD HGD - Spitz Lab

About the Department

The Spitz lab forms a dynamic and interdisciplinary team using cutting-edge functional genetic and genomic technologies together with computational approaches to understand how changes in our genome and chromatin structure contribute to human developmental abnormalities, cancers, and to vertebrate evolution. Using cellular and animal models, we study how the dynamic gene regulatory programs that govern embryonic development and tissue formation are encoded in the genome, and how (epi)genomic abnormalities or genetic mutations interfere with their deployment and lead to altered cell fate. We are integrated within the Department of Human Genetics in the Hyde Park campus. The Human Genetics Department offers a highly collaborative and supportive research environment to study the genetic and genomic underpinnings of human health and disease, with a strong emphasis on quantitative and statistical genetics, functional genomics and computational biology.

Job Summary

The Spitz lab is seeking a candidate interested in the field of functional genetics and genomics for a Research Technician position. We aim to understand the epigenomic basis of the programs that control embryonic development and to understand how genomic alterations can derail these programs and lead to developmental malformations or pediatric tumors. For this we combine cutting-edge genomic technologies (Hi-C, ChIP-Seq/Cut&Run, ATAC-Seq), spatially resolved-single-cell transcriptomics, and functional genetics in engineered cell lines and mouse models.

The successful candidate will perform and assist with wet lab experiments, which includes iPS cell culture, genomic engineering and analysis by single-cell genomic technologies of modified cell lines and mouse embryos. Depending on experience, the position may offer opportunities to develop an autonomous research project.


  • Contributes to the conduct of scientific research projects and to the organization of the lab's research activities.
  • Under supervision, the research technician will perform and assist cell culture and cell engineering (Crisp/Cas9) experiments using human iPS cells and cancer cell lines.
  • Helps maintain part of our mouse colony (managing breeding and genotyping).
  • Performs and assists genomic experiments, including chromatin profiling (ChIP-Seq, Cut&Run, ATAC-Seq) and conformation assays (Hi-C), single-cell transcriptomics.
  • Interprets data with help of lab members.
  • Participates in laboratory meetings and functions.
  • Provides logistical support for routine lab organization (stocks and ordering).
  • Analyzes and maintains data and/or specimens. Conducts literature reviews. Assists with preparation of reports, manuscripts and other documents.
  • Maintains technical and administrative support for a research project.
  • Performs other related work as needed.

Minimum Qualifications

Minimum requirements include a college or university degree in related field.
Work Experience:

Minimum requirements include knowledge and skills developed through ---


Preferred Qualifications

  • Bachelor's degree in biology, biochemistry, or related field.

  • Previous research experience in a laboratory setting. Previous experience with genomics, cell culture or mouse models would be an asset.

Preferred Competencies
  • Ability to work autonomously, to prioritize and manage workload to meet critical project milestones and deadlines.
  • Ability to follow and troubleshoot experimental research protocols.
  • Ability to work in a collaborative team environment.
  • Excellent organizational skills and attention to detail. Excellent communication skills.

Working Conditions
  • Lab environment.

Application Documents
  • Resume/CV (required)
  • List of three references (required)

When applying, the document(s) MUSTbe uploaded via the My Experience page, in the section titled Application Documents of the application.

Job Family


Role Impact

Individual Contributor

FLSA Status


Pay Frequency


Scheduled Weekly Hours


Benefits Eligible


Requires Compliance with University Covid-19 Vaccination Requirement


Drug Test Required


Health Screen Required


Motor Vehicle Record Inquiry Required


Posting Statement

Employees must comply with the University's COVID-19 vaccination requirements. More information about the requirements can be found on the University of Chicago Vaccination GoForward.

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange.

All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.

This job has expired.

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