Research Specialist C (Department of Dermatology)
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Posted Job Title
Research Specialist C (Department of Dermatology)
Job Profile Title
Research Specialist C
Job Description Summary
Our research group uses traditional and advanced tissue engineering approaches to address fundamental biologic questions related to the structure and function of normal and malignant skin tissue. Projects are designed to advance foundational knowledge that informs rational design of new targeted therapeutics. We have a particular interest in understanding how biologic sex impacts cancer. We also devote significant effort to preclinical IND-enabling efficacy and toxicity studies to advance our discoveries toward human trials. We have opportunities for experienced research technicians to contribute to these efforts using in vitro and in vivo cancer models. Expertise in cell signaling, human tissue culture, and standard molecular biology techniques including cloning, western blotting, and PCR are desired. The research specialist will have opportunity to work on their own project, in addition to helping other ongoing projects in the lab, and helping with general lab organization.
Job Description
Our research group uses traditional and advanced tissue engineering approaches to address fundamental biologic questions related to the structure and function of normal and malignant skin tissue. Projects are designed to advance foundational knowledge that informs rational design of new targeted therapeutics. We have a particular interest in understanding how biologic sex impacts cancer. We also devote significant effort to preclinical IND-enabling efficacy and toxicity studies to advance our discoveries toward human trials. We have opportunities for experienced research technicians to contribute to these efforts using in vitro and in vivo cancer models. Expertise in cell signaling, human tissue culture, and standard molecular biology techniques including cloning, western blotting, and PCR are desired. The research specialist will have opportunity to work on their own project, in addition to helping other ongoing projects in the lab, and helping with general lab organization.
Responsibilities/Duties
- Maintain cultures of primary human skin cells and skin cancer cell lines
- Determine the relative activity of anticancer agents on cancer cells in vitro
- Determine the activity of anticancer agents on tumors in vivo using mouse models
- Use modern in vitro biosensor assays to define G Protein Coupled Receptor Signaling in vitro
- Use standard lentiviral transduction approaches to define function of cancer associated oncoproteins
- Develop expertise in skin tissue engineering (we will provide the specialized instruction needed for this)
- Help maintain lab organization including orders, as well as maintain animal protocol compliance
- Perform additional duties as assigned
Qualifications
Bachelor's Degree with 3-5 years of related experience in research, clinical study, project and people management or equivalent combination of education and experience is required
Working Conditions
Office, Library, Computer Room; Requires extensive safety Physical Effort Typically sitting at a desk or table; Occasional lifting 25 lb. or less
This position is contingent upon funding.
Job Location - City, State
Philadelphia, Pennsylvania
Department / School
Perelman School of Medicine
Pay Range
$43,919.00 - $66,183.00
Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile.
Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
University Benefits
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